08-MusclesS11b - Muscular system Chapter47/lecture 8 Muscle...

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Muscular system Chapter47/lecture 8
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Muscle structure Figure 47.10
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Muscle structure Muscle: fascicles bundled together Fascicle: muscle fibers bundled together Muscle fiber: muscle cell
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Structure of myofibrils Myofibril proteins organized in to structures called: sarcomeres Sarcomeres comprised of Thin filaments: actin Thick filaments: myosin Actin/myosin interactions produce contraction Troponin & tropomyosin
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Sarcomeres Sarcomere: area between two Z lines Is the basic subunit of muscle contraction Alternating light and dark bands
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Sliding filament model A muscle contracts and shortens because myofibrils contract and shorten
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Muscle contraction Figure 47.14 0.5 micrometers shortening distance But 200,000 sarcomeres end-to-end can result in 8 cm shortening distance
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Molecular events of contraction Muscle contraction: cross-bridge cycle Start with myosin head bound to ATP but not to actin (relaxed muscle) Myosin hydrolyzes ATP == ADP + P1
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This note was uploaded on 04/25/2011 for the course BIOL 111 taught by Professor Dr.zielinski during the Spring '08 term at Purdue University-West Lafayette.

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08-MusclesS11b - Muscular system Chapter47/lecture 8 Muscle...

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