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Lecture 16 - Lecture 16 Tobacco Nicotine Historical Issues...

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Lecture 16 Tobacco & Nicotine; Historical Issues, Addiction Key Concepts Cigarettes portable drug delivery system Tobacco as a commodity Constituents of cigarette smoke pyrolysis products, organic matter, nicotine alkaloids, nitrosamines, benzopyrene Cardiovascular effects of cigarette smoke and nicotine Health risks of smoking (COPD, lung cancer)
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A bit of McGill history
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Tobacco Historical Issues Nicotine is an alkaloid isolated from NICOTIANA TABACUM in 1828 Introduced to Europe and Asia from the Americas by Portuguese who sailed with Columbus. Widely used by North and South American natives. Portuguese sailors introduced tobacco seeds to India, Japan, China, Brazil 1611 first exports to Europe of a mild Virginia tobacco became major cash crop in high demand. By 1614 there were more than 7,000 tobacco shops in London and a chronic tobacco shortage. It was generally believed to expel body toxins, neutralize drunkeness and prevent the plague
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Historical Issues 2 1690 s tobacco was becoming a major export product for the Americas. Slave trade grew up
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