Lecture 13 - Lecture 13 Psychostimulant Wrap-Up The Role of...

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Lecture 13 Psychostimulant Wrap-Up The Role of Dopamine in Motivation & Conditioning
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Key Concepts what is the role of dopamine in drug reward and addiction? (evidence presented to date) cues associated with reinforcers, the role of dopamine (Schultz et al., 1998) cue-induced reinstatement of drug-seeking (relapse model in animals) HBO Film on relapse with Anna Rose Childress) blockade of cue-induced relapse in animal models by dopamine D3 antagonists (SB277011-A) , as well as D3 partial agonists (e.g. BP897) (Gal & Gyertyan, 2006) limbic circuitry dopamine and incentive motivation
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