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Unformatted text preview: Phgy210 Gastric System 9 22:52 As a result of the secretory activity of salivary, gastric, pancreatic, hepatobiliary secretions, Carbohydrates. Polysaccharide disaccharide (amylase) Disaccharides monosaccharides Proteins. Proteins small peptides (pepsin, trypsin, chymotrypsin) Small peptides aa, di/tripeptides Fats. Fats mono, diglycerides, FAs (lipase, co-lipase, bile salts) The entire intestinal mucosa is characterized by crypts and villi. The vilus and crypt regions are continuous. The cells in the vili migrate and originate from the crypt. Rapidly dividing cells, high turnover rate (3-5d). On top, villus, below crypts of Lieberkuhn. Functional difference : Crypts o No digestive enzymes o Fluid secreters (3L/day) Alkaline fluid Succus Entericus Isotonic fluid. Contains ions : Na+, K+, Cl-, HCO3- Higher concentration of bicarbonate, which causes the high pH (7.5 to 9) Vili o Perform absorption o Complete digestion o Have digestive enzymes o Do not secrete fluid The cells, form the crypts, mature as they migrate up to villus region. At the tip, they die and slough into lumen. The villiar cells synthesize the enzymes but they die and slough into lumen....
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- Spring '08