Phgy 210 – Gastric System 2

Phgy 210 – Gastric System 2 - 18:28...

Info iconThis preview shows pages 1–2. Sign up to view the full content.

View Full Document Right Arrow Icon
Phgy 210 – Gastric System 2 18:28 Again, the propulsive/secretory/absorptive activities are all integrated for high  functional efficiency by neural and hormonal mechanisms.  The hormonal regulation : Non-GIT hormones may influence growth and dev’t of GIT. o No regulation of the function per se, however. GIT hormones may influence activities outside of the GIT. o Hypothalamic feeding centre receives stimulation by Ghrelin, increasing  appetite and stimulating hunger. On the contrary, leptin, secreted by fat  cells, will induce satiety, decreasing the appetite. GIT hormones which regulate activities INSIDE of the GIT Hormonal regulation of gut activity DES : Diffuse Endocrine System.  o Scattered in the mucosa. o Largest, most diversified endocrine system in the body. o The four most important are : Gastrin CCK Secretin GIP o The other hormones are referred to as candidate hormones. The gut regulatory hormones are  all  peptides. Released from the mucosa into  the portal blood, they pass through the liver (where they may undergo  modification), then into the systemic circulation where they well get to their target  cells. They have multiple targets : excitatory or inhibitory effects. 
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 2
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 04/26/2011 for the course PHGY 210 taught by Professor Trippenbach during the Spring '08 term at McGill.

Page1 / 6

Phgy 210 – Gastric System 2 - 18:28...

This preview shows document pages 1 - 2. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online