Phgy 210 – Gastric System 2

Phgy 210 – Gastric System 2 -...

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Phgy 210 – Gastric System 2 18:28 Again, the propulsive/secretory/absorptive activities are all integrated for high  functional efficiency by neural and hormonal mechanisms.  The hormonal regulation : Non-GIT hormones may influence growth and dev’t of GIT. o No regulation of the function per se, however. GIT hormones may influence activities outside of the GIT. o Hypothalamic feeding centre receives stimulation by Ghrelin, increasing  appetite and stimulating hunger. On the contrary, leptin, secreted by fat  cells, will induce satiety, decreasing the appetite. GIT hormones which regulate activities INSIDE of the GIT Hormonal regulation of gut activity DES : Diffuse Endocrine System.  o Scattered in the mucosa. o Largest, most diversified endocrine system in the body. o The four most important are : Gastrin CCK Secretin GIP o The other hormones are referred to as candidate hormones. The gut regulatory hormones are  all  peptides. Released from the mucosa into  the portal blood, they pass through the liver (where they may undergo  modification), then into the systemic circulation where they well get to their target  cells. They have multiple targets : excitatory or inhibitory effects. 
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Phgy 210 – Gastric System 2 -...

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