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16_Lecture_Part2_post - DNA Replication Getting Started The...

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DNA Replication: Getting Started The copying of DNA is remarkable in its speed and accuracy More than a dozen enzymes and other proteins participate in DNA replication Replication begins at particular sites called origins of replication , where the two DNA strands are separated, opening up a replication “bubble” A eukaryotic chromosome may have hundreds or even thousands of origins of replication Replication proceeds in both directions from each origin, until the entire molecule is copied
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Figure 16.12a (a) Origin of replication in an E. coli cell Origin of replication Parental (template) strand Double- stranded DNA molecule Daughter (new) strand Replication fork Replication bubble Two daughter DNA molecules 0.5 m
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