Ch 16%2617- learning objectives

Ch 16%2617- learning objectives - CHAPTER 16 THE MOLECULAR...

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CHAPTER 16 THE MOLECULAR BASIS OF INHERITANCE DNA as the Genetic Material 1. Explain why researchers originally thought protein was the genetic material. 2. Explain how the experiments performed by the following scientists provided evidence that DNA is the genetic material: a. Frederick Griffith b. Alfred Hershey and Martha Chase c. Erwin Chargaff 3. Explain how Watson and Crick deduced the structure of DNA and describe the evidence they used. Explain the significance of the research of Rosalind Franklin. 4. Describe the structure of DNA. Explain the base-pairing rule and describe its significance. DNA Replication and Repair 5. Describe the semiconservative model of replication and the significance of the experiments of Matthew Meselson and Franklin Stahl. 6. Describe the process of DNA replication , including the role of the origins of replication and replication forks. a. Explain the role of DNA polymerases in replication. b. Explain what energy source drives the polymerization of DNA. c. Distinguish between the leading strand and the lagging strand . d. Explain how the lagging strand is synthesized even though DNA polymerase can add nucleotides only to the 3’ end. Describe the significance of Okazaki fragments . e.
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This note was uploaded on 04/30/2011 for the course BIOL 1362 taught by Professor Loeblich during the Spring '08 term at University of Houston.

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Ch 16%2617- learning objectives - CHAPTER 16 THE MOLECULAR...

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