Chemistry 2213a Midterm Test, Fall 2009 Page 1 1. The biggest news story of the year is undoubtedly on influenza H1N1. The gold standard for the prophylaxis and treatment of influenza H1N1 is oseltamivir(Tamiflu), shown below. Which functional group is not present in oseltamivir? A) Ether B) Amine C) Amide D) Ester E) Ketone 2. Refer again to the structure of oseltamivir shown above. How many sp2-hybridized carbonatoms are present in oseltamivir? 3. Refer to the structure of oseltamivirshown below. Which of the indicated bonds can undergo free, unrestricted 360° rotation about the bond? ONHONH2OOoseltamivirONHONH2OOIIIIIIIVV
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