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Unformatted text preview: Breaking vs. Making Fatty Acids: It’s Just Not the Same…! They occur by different processes They utilize different enzymes They occur in different cellular They compartments compartments They exploit different size “unit blocks”: 2carbon for breakdown, 3-carbon for building carbon And these ensure that they happen at And different times… different
11.4.06 1 Biotin and CO2 (again…) 2 Fig. 21-1 A trifunctional protein: trifunctional acetyl-CoA carboxylase acetyl-CoA One subunit carries the One biotin, attached via the ε -amino group of a -amino lysine residue lysine One subunit activates One CO2 by transferring it to CO the biotin the Which serves as a long Which flexible arm to carry the CO2 to the third subunit CO 11.4.06 Acetyl-CoA Activation: Making Malonyl This third subunit, a This transcarboxylase, does exactly that: transfers the CO2 to acetyl-CoA, the converting it into malonyl-CoA, to be used in the next step of the reaction of
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