ch08 - 3/7/2011 1 Nucleotides and Nucleic Acids Chapter 8...

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Unformatted text preview: 3/7/2011 1 Nucleotides and Nucleic Acids Chapter 8 DNA molecules can be GIANT 3/7/2011 2 The Hershey-Chase experiment proves DNA is the genetic material 8-1 Nucleotide Nucleotide building blocks 1. Nitrogenous bases 2. Ribose, or dexoyribose; base + sugar =nucleoSIDE 3. Phosphate. Nucleoside+phosphate(s) = nucleoTIDE 3/7/2011 3 8-2 The nitrogenous bases come in two families. These can be added to two 5- carbon sugars, ribose or 2 deoxy ribose. 8-4 Nucleotides named as phosphate derivatives of nucleotides 3/7/2011 4 8-3b The sugar rings assume one of two main conformations This is common form for B DNA This common form for RNA (A form helix) 9 1 8-4 N-glycosidic bond 3/7/2011 5 The base can assume several conformations with respect to the ribose ring The anti form is more stable. 8-5 Some nucleic acids contain rare, modified bases 3/7/2011 6 8-7 Nucleic acid polymers Why is DNA resistant to base-hydrolysis?...
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ch08 - 3/7/2011 1 Nucleotides and Nucleic Acids Chapter 8...

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