ch14,15(gluconeo)n2-jdr

ch14,15(gluconeo)n2-jdr - A stripped down Figure of...

Info iconThis preview shows pages 1–13. Sign up to view the full content.

View Full Document Right Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: A stripped down Figure of Glycolysis 14-3 Alternate Fates of Pyruvate Reaction 11a If little oxygen is available, LDH reduces pyr to lactate and reoxidizes NADH GAPD p. 547 Homolactic fermentation regenerates NAD+ for GAPD Reaction 11a In yeast, alcoholic fermentation is an alternative to lactate formation Reaction 11b 14-13 Hydride (H- ) nucleophilically attacks electrophilic carbonyl C Reaction 11c If O 2 is available, pyruvate can be imported to the mitochondria and dealt with by PDC. This will be discussed later. Other sugars feed into glycolysis Lactase expression can be repressed, depending on environment. This is basis for lactose intolerance . Fructose goes to F6P in muscle and kidney. It is converted to F1P in the liver, which has little hexokinase. Fructose intolerance often associated with low aldolase B. Galactose Galactosemia Gluconeogenesis The ability to synthesize glucose is important to mammals since certain tissues, particularly brain and RBC, are almost solely dependent on glucose as an energy source. In normal humans, under fasting conditions, 80% of glucose is consumed by brain. The glycogen reservoir in liver has only 1/2 day supply for the brain. In periods of dietary glucose deprivation, we must be able to make glucose from other sources. The Cori cycle. Gluconeogenesis:...
View Full Document

This note was uploaded on 05/01/2011 for the course CH 53890 taught by Professor Raymonds during the Spring '09 term at University of Texas.

Page1 / 33

ch14,15(gluconeo)n2-jdr - A stripped down Figure of...

This preview shows document pages 1 - 13. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online