12_6_2010_The immune system_notes

12_6_2010_The immune system_notes - 12-6-2010 The immune...

Info iconThis preview shows pages 1–4. Sign up to view the full content.

View Full Document Right Arrow Icon
1 12-6-2010 – The immune system Learning Objectives: t Describe the function of the animal immune system; t Explain the difference between innate and adaptive immunity; t Describe the primary events associated with the innate immune response and the building of adaptive responses. Defenses against pathogens t Body’s defenses are integrated: t Innate immunity: t Rapid response, but generic t Involves recognition of invading pathogens t Uses both cells and soluble antimicrobial proteins t Adaptive immunity t Slower response but highly specific t Characterized by genetic rearrangements that generate a diverse set of molecules to recognize any invader
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
2 The skin t Largest organ of the body t Provides a nearly impenetrable barrier t Oil and sweat glands give skin a pH of 3–5 t The skin produces lysozyme, which breaks bacterial cell walls t Also contains normal flora t Nonpathogenic microorganisms that out-compete pathogenic ones Other pathogen access routes t Digestive, respiratory, and urogenital tracts t All 3 lined by epithelial cells t Cells secrete mucus which traps microbes t Digestive tract t Salivary lysozyme; acidic stomach t Nonpathogenic normal flora t Respiratory tract t Ciliary action t Urogenital tract t Acidic urine, normal flora
Background image of page 2
3 Microbes Bacterial, fungal components Viral RNA, DNA, protein Virus What do they have in common? t Signature molecules, or parts of molecules, which are unique to microbes; t These represent the basis for distinguishing what is “ self ” from what is “ non-self ”; t Primary function of the immune system! Innate immunity
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 4
This is the end of the preview. Sign up to access the rest of the document.

Page1 / 14

12_6_2010_The immune system_notes - 12-6-2010 The immune...

This preview shows document pages 1 - 4. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online