Lecture 10 - mRNA Ribosome Transfer RNA Amino acids The...

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BIOL104-04 Principles of Biology September 15, 2010 Lecture #10 Ch 15 Genes & How They Work
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DNA Polymerase III Requires a Template and a Primer
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Proteins Required for DNA Replication Helicase Single-strand DNA-binding protein (SSB) Gyrase Primase DNA Polymerase III
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Gyrase
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The Lagging Strand Problem
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DNA Polymerase I DNA Ligase
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Replication of a Bacterial Chromosome
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Replication of Eukaryotic Chromosomes Linear molecule Multiple points of origin Telomeres - special regions at the end of the linear molecule Telomerase - special enzyme needed to help maintain the ends of chromosomes
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Central Dogma of Cell Biology
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Transcription makes an RNA copy of DNA Coding (sense) 5’-TCAGCCGTCAGCT-3’ DNA Template (antisense) 3’-AGTCGGCAGTCGA-5’ DNA ! Transcription ! Coding 5’-UCAGCCGUCAGCU-3’ RNA
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Translation uses information in RNA to synthesize proteins • Takes place on the ribosome • Needs the following
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Unformatted text preview: mRNA Ribosome Transfer RNA Amino acids The Genetic Code How does the DNA sequence code for proteins? Cracking the code How many bases make a word? How many bases code for a single amino acid? How can 4 nucleotides code for 20 amino acids? The Triplet Code Understanding the reading frame The fat cat ate the rat Hef atc ata tet her at Addition or deletion of a base Throws off the reading frame Results in a completely different sequence of amino acids Non-function protein Mutation happens in the DNA What does mRNA look like? What does mRNA look like? What does mRNA look like? In-Class Activity Analyzing Genes From Genes to Proteins handout Next time Finish Ch 15 Transcription & Translation Exam on Monday Bring No. 2 pencil Bring Student ID...
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Lecture 10 - mRNA Ribosome Transfer RNA Amino acids The...

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