Bacteria_Exam_2010-1

Bacteria_Exam_2010-1 - not a term for genetic variation in...

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1 YOUR NAME: ………………………………………………………………………… BIOL 497A. Evolution of Infectious Disease: Exam 2 A total of 33 marks in 75 minutes (17 questions): April 2010 1. What is unusual about the genome of Salmonella typhi ? (2 marks) 2. What factors have enabled the recent rise and spread of Mycobacterium tuberculosis ? (2 marks) 3. What are flagella? (1 mark) 4. Give two pieces of evidence for the occurrence of lateral gene transfer (LGT) in bacteria. (2 marks) (i) (ii)
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2 5. What are mutators and why could they be important in bacterial evolution? (2 marks) 6. Outline two reasons why the Buchnera bacteria are important for studies of bacterial evolution. (2 marks) (i) (ii) 7. Outline the contrasting models for the origin and evolution of Mycobacterium tuberculosis. (2 marks) 8. With respect to bacteria, what is motility? (1 mark) 9. Explain the differences between transformation and transduction. (2 marks)
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3 10. Which of these is
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Unformatted text preview: not a term for genetic variation in bacteria? (1 mark) (i) strain (ii) quasispecies (iii) genocloud (iv) serogroup 11. What is the lipopolysaccharide and why is it important in bacterial virulence? (2 marks) 12. What are the biovars of Yersinia pestis and why have they been claimed be important for understanding the history of the plague? (2 marks) 13. What are the major differences between Neisseria meningitidis and Neisseria gonorrhoeae ? (2 marks) 4 14. Describe some of the factors that have enabled the rise of antibiotic resistance in bacteria. (3 marks) 15. List two differences between bacteria and eukaryotes (2 marks) (i) (ii) 16. With respect to E. coli ; (2 marks) (i) What disease syndrome is associated with E. coli O157:H7? (ii) What do the O and H terms refer to? 17. Describe, in as much detail as you can muster, the evolutionary history of one bacterial species. (3 marks) 5...
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Bacteria_Exam_2010-1 - not a term for genetic variation in...

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