PSY 356 antidepressants 3

PSY 356 antidepressants 3 - ANTI-DEPRESSANTS CONTINUED At...

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ANTI-DEPRESSANTS CONTINUED At the cortex has beta NE receptors (does not have alpha 2 receptors) -When LC is hyper responsive, there is a regional difference of NE levels NE levels are low at soma, cell body of LC NE level is high at projection sites, terminals of LC Input of LC (ventral bundles) are the stress sensitive inputs that are disrupted -everything happen (LC hyperactivity) because of lack of NE NE levels are higher in post synaptic than presynaptic cleft LC is responsible for processing information (like sensory info) NE is responsible for sound to noise ratios (S/N ratio) -modulates the spontaneous activity (input that excites the cortex -signal or evoked activity) Signal is to noise as evoked activity is to spontaneous activity (background) -cortex is trying to pick up important info from all of the background noise -by increasing signal strength you can pick it out from the background, decrease background noise for signal to pop out . NE suppresses the background noise in the cortex (on Beta 1's or Beta 2's -inhibitory for background so noise
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This note was uploaded on 05/05/2011 for the course PSY 356 taught by Professor Simson during the Spring '11 term at Miami University.

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PSY 356 antidepressants 3 - ANTI-DEPRESSANTS CONTINUED At...

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