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PSY 356 antidepressants 4

PSY 356 antidepressants 4 - A NTI DEPRESSANTS CONTI NUED...

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ANTI DEPRESSANTS CONTINUED Treatment for depression a. Three classic treatments 1. Side-effects a. All inadvertently block the Ach mus receptor i. Producing odd side effects b. All are histamine blockers (drowsiness) c. Slight chance that you could die from arrhythmia 2. MAO inhibitors -work by inhibiting the enzymze that breaks down dopamine serotonin and norepinephrine (catechol amines) which as known as monoamines a. Once the transmitter is in the vesicle, it is safe from breakdown b. Lock onto MAO -bind to MAO and prevent it from workings therefore monoamines increase in the synapse i. Will trigger down regulation c. Take two to three weeks to start reversing signs of depression d. Parnate -these MAOIs -suicide inhibitors -once they are bound to MAO, the will never let go until there is a new enzyme that is produced -they are irreversible e. Problematic and sometimes lethal side effects f. Must be very careful about diet i. Sympathoamines -monoamines in food i.
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  • Spring '11
  • SIMSON
  • Selective serotonin reuptake inhibitor, Antidepressant, Monoamine Oxidase Inhibitor, NE vs, reuptake blocker

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