1-27 - BCMB422: Computational Biology/Protein Modeling (5)...

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Hong Guo F223 WLS BCMB University of Tennessee hguo1@utk.edu, 865-974-3610 Jan. 27, 2011 BCMB422: Computational Biology/Protein Modeling (5)
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3D Structures of HIV-1 Protease  complexed with different inhibitors (1) Open 1HIV.pdb in Z:/bcmb422/1-13 (Crystal structure of a complex of HIV-1 protease with A dihydroethylene-containing Inhibitor with PDB ID: 1HIV). There are many HIV-1, inhibitor complexes for which the structures have been determined. Go to http://www.rcsb.org/pdb/search/advSearch.do And type “HIV-1 protease” under “structure Title” Protease- Inhibitor interactions at the binding site
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3D Structures of HIV-1 Protease  complexed with different inhibitors (2) Protease- Inhibitor interactions 3.5 3BXS.pdb 3EKV.pdb Try yourself
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Λ repressor operator complex Use Pull-down Menu: MOE->File->Open to open file 1LMB.pdb in z:/bcmb422/1-13. Highlight Hydrogen Bonds. Protein, DNA Interactions (1) Two helix-turn-helix motifs contribute to the binding Recognition helix
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Protein, DNA Interactions (2) Show the residues and interactions that contribute to the recognition of DNA
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This note was uploaded on 05/05/2011 for the course BIOL 400 taught by Professor Dr.biology during the Spring '11 term at University of Tennessee.

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1-27 - BCMB422: Computational Biology/Protein Modeling (5)...

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