Notes - Brad Binder [email protected] Office hours: Monday &...

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1 Brad Binder [email protected] Office hours: Monday & Wednesday 9-10 AM or by appointment Hesler 343 Readings in Textbook : pages 326-337 pages 340-345 pages 351-357 Practice Problems : •Pages 349-350: Problems- #4, #6, #7, #9, #11, #12 •Page 379- #1 Explore Lipids and Membranes Explore Membrane Concepts Some Key Ideas: Fatty Acids used for energy storage, part of membranes, signal transduction In aqueous environment form micelles Membrane Lipids Form bilayers 3 Main types of membrane lipids: Glycerophospholipids Sphingolipids (phosphosphingolipids, glycosphingolipids) Cholesterol Membranes Semipermeable Also contain proteins and sugars Fluid Mosaic Model Movement of Substances Across the Membrane Active vs. Passive Pumps vs. Channels Energy for Active transport can come from several sources ATPases Antiporters Symporters Uniporter Fatty Acids, Lipids, Membranes
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2 Fatty acids Amphipathic: polar headgroup (carboxyl) and a nonpolar tail (hydrocarbon) 16:0 18:1 cis- Δ 9 nonpolar tail Polar headgroup Palmitate: saturated lipid 16 C’s and no double bonds Oleate: unsaturated lipid 18 C’s and one cis double bond C9-C10 Fatty acids A fatty acid with a particular C# and unsaturations can have several names These are important components of our diet In aqueous media fatty acids form a sphere called a micelle Fatty acids
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3 3 main types of lipids in biological membranes based on backbone: Glycerophospholipids Sphingolipids (sphingophospholipids and sphingoglycolipids) Cholesterol Membrane Lipids: glycerophospholipids Membrane lipids are amphipathic esters of an alcohol backbone and fatty acids Most common membrane lipids use glycerol as the backbone alcohol Glycerophospholipids contain two nonpolar fatty acid esters and a polar phosphate head group
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This note was uploaded on 05/05/2011 for the course BIOL 400 taught by Professor Dr.biology during the Spring '11 term at University of Tennessee.

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Notes - Brad Binder [email protected] Office hours: Monday &...

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