20-21glycolysis

20-21glycolysis - 1 Some concepts well cover: General...

Info iconThis preview shows pages 1–4. Sign up to view the full content.

View Full Document Right Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: 1 Some concepts well cover: General Metabolism Concepts Strategies that cells use to make a thermodynamically unfavorable reaction occur ATP- the chemical currency of the cell (energy charge) Vitamin-derived co-factors Glycolysis 3 Phases Irreversible Steps vs. committed step Substrate level phosphorylation Regulatory Mechanisms Gluconeogenesis Compartmentalization of the pathway Irreversible Steps Regulatory Mechanisms Reciprocal Regulation Futile Cycles Readings in Textbook : pages 409-415 pages 420-430 pages 433-449 pages 452-456 pages 458-468 Practice Problems : Pages 431-432- problems # 1,5,8,13 Pages 473-474- problems # 2,9,10,11,14 Explore Glycolysis Explore Gluconeogenesis Metabolic Pathways in the Cell 2 Thermodynamics of biological reactions- Review Whether a reaction will occur spontaneously or not depends on two parameters: A + B C + D A][B] [ C][D] [ log G G o' RT example: Chemical Energy Currency in the cell is phosphate based + H 2 O O P OH O O-- + P i + H 2 O + PP i O P O P OH O O- O O-- G o = -30.5 kJ/mol G o = -45.6 kJ/mol Reactions using energy coupling often involve the hydrolysis of adenosine triphosphate (ATP) ATP is kinetically stable so it can be stored until needed ATP is an activated carrier of phosphoryl groups because transfer from of phosphoryl group is exergonic 3 Coupling ATP hydrolysis with formation of Glucose-6-Phosphate: ATP is constantly being made and utilized in a living system...
View Full Document

Page1 / 15

20-21glycolysis - 1 Some concepts well cover: General...

This preview shows document pages 1 - 4. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online