Lecture 13 - The catalytic triad in chymotrypsin Catalytic

Info iconThis preview shows pages 1–7. Sign up to view the full content.

View Full Document Right Arrow Icon
Catalytic Mechanism:Chymotrypsin Peptide hydrolysis is an inherently slow reaction Enzymes employ several strategies to catalyze reactions specifically – covalent catalysis is an important strategy Example of covalent strategy is peptide hydrolysis by the enzyme chymotrypsin
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Catalytic Mechanism:Chymotrypsin Chymotrypsin has a highly reactive serine in the active site
Background image of page 2
Catalytic Mechanism:Chymotrypsin
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 4
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 6
Background image of page 7
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: The catalytic triad in chymotrypsin Catalytic Mechanism:Chymotrypsin Peptide hydrolysis mechanism by chymotrypsin Catalytic Mechanism:Chymotrypsin Specificity of the chymotrypsin reaction Catalytic Mechanism:Chymotrypsin Catalytic triads in other chymotrypsin-like enzymes Catalytic Mechanism:Chymotrypsin Oxyanion hole in other chymotrypsin-like enzymes...
View Full Document

This note was uploaded on 05/05/2011 for the course BIOL 400 taught by Professor Dr.biology during the Spring '11 term at University of Tennessee.

Page1 / 7

Lecture 13 - The catalytic triad in chymotrypsin Catalytic

This preview shows document pages 1 - 7. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online