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Lecture 13 - The catalytic triad in chymotrypsin Catalytic...

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Catalytic Mechanism:Chymotrypsin Peptide hydrolysis is an inherently slow reaction Enzymes employ several strategies to catalyze reactions specifically – covalent catalysis is an important strategy Example of covalent strategy is peptide hydrolysis by the enzyme chymotrypsin
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Catalytic Mechanism:Chymotrypsin Chymotrypsin has a highly reactive serine in the active site
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Catalytic Mechanism:Chymotrypsin
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Unformatted text preview: The catalytic triad in chymotrypsin Catalytic Mechanism:Chymotrypsin Peptide hydrolysis mechanism by chymotrypsin Catalytic Mechanism:Chymotrypsin Specificity of the chymotrypsin reaction Catalytic Mechanism:Chymotrypsin Catalytic triads in other chymotrypsin-like enzymes Catalytic Mechanism:Chymotrypsin Oxyanion hole in other chymotrypsin-like enzymes...
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