Lectures1and2 - c) van der Waals interactions d)...

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STUDY OF BIOCHEMISTRY Concepts of chemistry are useful in explaining properties of biological molecules Interactions between biological molecules via chemical reactions are crucial in control and regulation of various metabolic functions connected to life. Biological molecules are made of building blocks such as amino acids, nucleic acids, carbohydrates, lipids
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STRUCTURE AND STABILITY OF BIOMOLECULES Covalent interactions help make up the structure of individual building blocks and are quite strong. e.g. C-C covalent bond - 1.54 Å with bond energy of 356 kJ/mol or 85 kcal/mol. Non-covalent interactions are weaker than covalent interactions. Four types of non-covalent bonds/interactions – a) Electrostatic interactions b) Hydrogen bond interactions
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Unformatted text preview: c) van der Waals interactions d) Hydrophobic interactions NONCOVALENT INTERACTIONS NONCOVALENT INTERACTIONS PROPERTIES OF WATER Water is highly polar. Interaction with other water molecules by hydrogen bonds. Water has a high dielectric constant. Can interact with other solutes via ionic interactions. Explore hydrogen-bond formati Explore flickering clusters Explore Bulk water NONCOVALENT INTERACTIONS Explore Hydrophobic effect Solvation of NaCl crystals in water ACID-BASE REACTIONS Biological processes need buffer systems to maintain constant pH. Buffers resist changes in pH when small amounts of acid or base are added. Acid-base reactions form the basis of buffer systems....
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Lectures1and2 - c) van der Waals interactions d)...

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