3 - HIV1GeneExpression:Possible RachelDunlap,Alexis...

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Click to edit Master subtitle style  5/5/11 Role of Histone Modification on  Transcriptional Regulation and  HIV-1 Gene Expression: Possible  Rachel Dunlap, Alexis  Williams, Hannah Gray, Hank  Walker, and Paolo Vignali
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 5/5/11 Epigenetics The study of heritable changes in phenotype  or gene expression caused by mechanisms  other than changes in the underlying DNA  sequence  These changes may remain through cell  divisions for the remainder of the cell’s life and  may last for multiple generations
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 5/5/11 Histones Highly alkaline proteins found in eukaryotic  cell nuclei that package and order the DNA  into structural units called nucleosomes They’re the the chief protein components of  chromatin, acting as spools around which  DNA winds, and they play a role in gene  regulation De-methylation H3 and H4 histones promote  silencing of host cellular genes, while in 
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 5/5/11
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 5/5/11 Acetylation and Deacetylation
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 5/5/11 Methylation and  Demethylation
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