LAB 9rev answer sheet for students

LAB 9rev answer - 10 Do any chromosomes lack alu sequences If so why might this be so 11 Some of the au sequences have not been placed Why might

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Biology 240 GENETICS LAB 9 – Answer Sheet Name____________________________________________ Student ID _______________________________________ EXERCISE 1 – HOW DO I FIND INFORMATION ABOUT GENES OR TRAITS OF INTEREST? 1. Where is the gene for LHON located? 2. Is there more than one mutation causing LHON? 3. What do genes associated with LHON code for and what is the normal function of the encoded genes? 4. Is penetrance of LHON affected by environmental factors? 5. How many base pair changes are there between your search sequence and a sequence for human mitochondrial DNA? 6. Are there matches to LHON on other human chromosomes? Which ones?
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7. Do the matches represent the complete ND1 sequence that you used for your blast search or only a partial sequence? 8. How good is the match with a sequence on chromosome 16? Could this match be due to random chance? If not, speculate on why this match exists. 9. Where are the best matches to LHON found? EXERCISE 2. TRANSPOSABLE ELEMENTS IN HUMANS
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Unformatted text preview: 10. Do any chromosomes lack alu sequences? If so, why might this be so? 11. Some of the au sequences have not been placed. Why might this occur? EXERCISE 3. FINDING THE GENE FOR COLORBLINDNESS 12. How many genes for color blindness are on the X chromosome? 13. How many introns are there in this gene and how long is the processed mRNA? 14. Move to the left of OPN1MW and find OPN1LW. How many introns does it contain? 15. Where is the gene for OPN1MW2? 16. Zoom in and provide below the first 12 bases of the OPN1MW gene. Translate these to the first 4 amino acids in the protein chain. 17. What information does this give you about the opsin genes on the X-chromosome (summarize)? 18. Speculate on the kinds of mutations that might result in colorblindness. 19. What does the tree say about the age of this gene sequence? Cite your evidence. 20. What organism has genes that are closest to human? Give scientific and common name....
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This note was uploaded on 05/05/2011 for the course BIOL 400 taught by Professor Dr.biology during the Spring '11 term at University of Tennessee.

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LAB 9rev answer - 10 Do any chromosomes lack alu sequences If so why might this be so 11 Some of the au sequences have not been placed Why might

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