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Unformatted text preview: In 1997, scientists in Dr. Peter Kim ’ s laboratory at the Whitehead Institute at MIT determined the core structure of the gp41 HIV envelope glycoprotein by protein x-ray crystallography. It is shown in a ribbon diagram representation below. The first (left) view is from the side. The second (right) view has been rotated 90 degrees about the horizontal in order to show its dimensions from the top. Use the information in the diagram to answer questions 19-20 below. 19. Which best describes this protein structure? a. α-helical b. antiparallel β sheet c. parallel β sheet d. mixed α-helix/ β sheet 20. Each of the six helices in this core structure is approximately the same length. Approximately how many amino acids make up the gp41 core structure? Answer: 9 turns per helix, 6 helices 9 x 6 = 54 turns. There are 3.6 amino acids per turn 54 x 3.6 = 194 amino acids....
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This note was uploaded on 05/07/2011 for the course CHEM 365 taught by Professor Huxford during the Spring '08 term at San Diego State.
- Spring '08