PrExam2A - Biology 352 Practice Exam 2a YOU MAY USE A...

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Biology 352 Practice Exam 2a 1 of 7 YOU MAY USE A CALCULATOR AND THE HANDOUT WITH ALL OF THE FORMULAS Questions 1-3 concern the data set below. The gene alcohol dehydrogenase was sequenced in 120 Drosophila melanogaster . Three different alleles were found. Allele Sequence Genotype Number of individuals A ATCCA C GTCGTCATCACT G AA 100 B ATCCA T GTCGTCATCACT G AB 17 C ATCCA C GTCGTCATCACT A AC 1 BB 2 1. What is the frequency of allele A? a. 0.417 b. 0.492 c. 0.833 d. 0.908 e. 0.983 2. What is the frequency of genotype AB? a. 0.085 b. 0.142 c. 0.170 d. 0.283 e. 0.340 3. What is the expected number of genotype AB, assuming Hardy Weinberg equilibrium? a. 9.3 b. 9.5 c. 15.9 d. 19.1 e. 38.2
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Biology 352 Practice Exam 2a 2 of 7 4. Mutation is a process that can a. create new genetic variation b. change allele frequencies over long periods of time c. change genotype frequencies over long periods of time d. A and B only e. A, B and C 5. In quantitative genetics, “heritability” is defined as a. the proportion of the total variation due to genetic differences, for the trait of interest. b. the number of genes that control the trait of interest. c. the expected heterozygosity for the trait of interest. d. the amount of inbreeding or assortative mating for the trait of interest. e. the number of different genotypes possible for the trait of interest. 6. Which of the following best describes the amount of genetic variation in natural populations? a. Most species are polymorphic at nearly every base pair position in the genome. b. Most species are polymorphic at the protein level for every gene we can look at. c. Outbreeding is necessary to maintain polymorphism at the level of the DNA and the protein. d. Most species have some polymorphism at the level of the DNA and the protein, unless they have been through severe bottlenecks in population size. e. In natural populations, almost all polymorphism is maintained by natural selection. 7. Look at the house on the right. Two populations of mice are monomorphic for two different alleles. All mice in the west wall are AA , and all mice in the east wall are aa . Mice can migrate into the middle area, but they are eaten by house cats before they reproduce. ( No breeding takes place in the house. Reproduction only takes place within the east wall an within the west wall.) It is impossible for a mouse to move all the way through the house and enter the opposite wall. If you sampled mice in the central part of this house, and had no knowledge of the hidden populations in the walls, what would you conclude? a. H e > H o b. H e < H o c. H e = H o = 2 pq d. H e = H o = 0 e. H e = H o and these values are between 0 and 2 pq .
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Biology 352 Practice Exam 2a 3 of 7 8. In humans, shoplifting can be caused by a rare allele in the anoni-W gene that is completely recessive. 1% of the population has the debilitating shoplifting phenotype caused by this gene. How many people are heterozygous carriers of the shoplifting allele? (Assume Hardy-Weinberg
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This note was uploaded on 05/07/2011 for the course BIOLOGY 352 taught by Professor Townsend during the Spring '08 term at San Diego State.

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PrExam2A - Biology 352 Practice Exam 2a YOU MAY USE A...

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