352_Outline10_S11 - Biology 352 Lecture 10 Spring 2011...

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Biology 352 Lecture 10 Spring 2011 1 LECTURE 10 : Genetic Variation and Polymorphisms in Populations I. Evolution. A. A central unifying concept in biology. B. Evolution : "Genetic changes in populations over time." 1. Evolution involves genetic change. 2. The population is the unit of evolution. C. Population : individuals of a species present at a specific geographic location. D. Populations have gene pools . II. Describing Gene Pools. A. Population genetics : study of how genes, alleles, and chromosomes behave in populations. 1. Largely a mathematical discipline. 2. Foundations formulated in the 1920's and 1930's. 3. Sir Ronald Fisher, J.B.S. Haldane, and Sewell Wright. B. Statistics for describing gene pools. 1. Genotypic frequencies : relative frequencies of genotypes for a single gene in a population. 2. Allele frequencies : relative frequencies of alleles for a single gene in a population. III. An example: MN red blood cell locus.
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Biology 352 Lecture 10 Spring 2011 2 A. The MN locus. 1 gene with codominant alleles M and N .
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352_Outline10_S11 - Biology 352 Lecture 10 Spring 2011...

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