Pathogen Project Pathogens Coccidioides immitus

Pathogen Project Pathogens Coccidioides immitus - Aerial...

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Unformatted text preview: Aerial Mycellium Causative agent: Coccidioides immitus Category: thermally dimorphic systemic fungus Kingdom: Fungi Phylum: Ascomycota Class: Euascomycetes Order: Onygenales Family: Onygenaceae Genus: Coccidioides Disease: Coccidioidomycosis - acquired from inhalation of the spores (arthroconidia). Once in the lungs, the arthroconidia transform into spherical cells called "spherules". An accute respiratory infection occurs 7 to 21 days after exposure and typically resolves rapidly. However, the infection may alternately result in a chronic pulmonary condition or disseminate to the meninges, bones, joints, and subcutaneous and cutaneous tissues. Morphology & Gram RX: Coccidioides immitis/posadasii colonies grow rapidly. The macroscopic morphology may be very variable. At 25 or 37°C and on Sabouraud dextrose agar, the colonies are moist, glabrous, membranous, and grayish initially, later producing white and cottony aerial mycelium. With age, colonies become tan to brown in color. Isolation involves innoculation the clinical material into IMA agar, BHI agar with 10% sheep's blood and a medium containing cyclohexamide and incubating at 30 degrees celcius. Cultures should be agar, BHI agar with 10% sheep's blood and a medium containing cyclohexamide and incubating at 30 degrees celcius....
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This note was uploaded on 05/11/2011 for the course BIO 31 taught by Professor Silva during the Spring '11 term at Reedley.

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