2.+Ch+15+Sex+Linkage+and+pedigree+analysis

2.+Ch+15+Sex+Linkage+and+pedigree+analysis - A Sex-Linked...

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Chromosomal Basis of Inheritance Linked genes Sex determination Genes on sex chromosomes Review of Transmission genetics
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Visualization of specific gene on human chromosomes preparation “in situ hybridization” Figure 15.1
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Thomas Morgan worked with Drosophila melanogaster Morgan first observed and noted Wild type, or normal, phenotypes that were common in the fly populations Traits alternative to the wild type Are called mutant phenotypes Figure 15.3
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Recombinant offspring Are those that show new combinations of the parental traits When 50% of all offspring are recombinants Geneticists say that there is a 50% frequency of recombination
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Map These Genes?
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Unformatted text preview: A Sex-Linked Trait in Drosophila Color Blindness is a Sex-Linked Trait The Chromosomal Basis of Sex • An organism’s sex – Is an inherited phenotypic character determined by the presence or absence of certain chromosomes Sex Determination in Humans • In humans and other mammals – There are two varieties of sex chromosomes, X and Y Figure 15.9a (a) The X-Y system 44 + XY 44 + XX Parents 22 + X 22 + Y 22 + XY Sperm Ova 44 + XX 44 + XY Zygotes (offspring) In-Text Art p. 207 In-Text Art p. 205 In-Text Art p. 206(1) In-Text Art p. 206(3) X-linked dominant inheritance Y-linked inheritance Sons inherit from father; females never affected....
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