BIS101-003_MT1_Key2

BIS101-003_MT1_Key2 - y/ Name VUQY- Sl'om Z BISlOl-003,...

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Unformatted text preview: y/ Name VUQY- Sl'om Z BISlOl-003, Spring 2011 Midterm I R. L. Rodriguez, Instructor April 20, 2011 Please print your name below and on each subsequent page. Your exam has 8 questions and 6 pages (including cover page and score sheet) Name 1. On the pedigree below, indicate the genotype (AA, Aa, aa and A») for each individual shown using the standard rule for pedigree analysis, (8 pts) A. What is type of inheritance pattern is shown below? (3 pts.) act/+050 Moei YCC—ess i v (1 B. What proportion of the brothers of the affected female will be carriers? (4 pts.) 2/3 2, Assume that in guinea pigs, dark brown fur (B) is dominant to black fur (b). If you mate a homozygous black guinea pig with a heterozygous brown guinea pig, what proportion of the progeny will be black? Circle the correct answer (8 pts.) A. None B. 1/4 13. All of the above. Name 3. From the possibilities shown below, indicate the antibody status of a person who has type 0 blood. Circle the correct answer. (8 pts.). (9 Both anti-A and antirB antibodies. B. Anti-B antibodies. C. No antibodies. D. AntiiA antibodies. E. No surface antigens. 4. Assume Y chromosome non-disjunction occurs in the second meiotic division during spermatogenesis. What are all the possible offspring that could result from the fertilization of normal eggs? Circle the correct answer. (8 pts.) Metamale son,Turner daughter, two normal daughters B. Turner daughter and two normal daughters and normal son C. Klinefelter son and two Turner daughters and a normal daughter D. Metamale son, Turner daughter, normal daughter, normal son 5. Sickle cell anemia is a recessive trait in humans. Ina mating between a father who has sickle cell anemia (53) and a mother who is heterozygous for the gene (SS), what is the probability that their first three children will be normal? Circle the correct answer (8 pts.) A.% B.1/2 (C) 1/8 D. None 6. Which of the following statements is not true about sister chromatids? Circle the correct answer(s) (8 pts.) (9 They segregate from each other at anaphase l of meiosis. B. They are attached to the same centromere. C. They segregate from each other at anaphase 2 of meiosis. @ They contain the same genes in the same order but may have different alleles of some genes. B. All of the above. Name 7. The genes agouti coat (a,) bent tail (b) and crimped ear (6) have been identified as belonging to the same linkage group in mice. Progeny mice are produced from a testcross with a mouse heterozygous for all three alleles. The following phenotypes are observed in the progeny of the test cross: 33‘,- + b L 330 / bent tail and crimped ear agouti coat and crimped car 95 agouti coat and bent tail 65 wild type 5 agouti coat 335 \ afi— 1— bent tail 90 crimped ear 70 agouti coat, bent tail, crimped ear fl 1000 From the data shown, what is the genotype of the F1 parent and tester parent? (6 pts.) “WA kbL o.++ kbc From the data shown, what is the genotype of the parents of the F1? (6 pts.) “flat, oet‘l‘ +bc (“UL Al”? From this data, what percentage of progeny is the result of double crossovers during meiosis? Circle the correct answer below. (5 pts.) (1) 15 ® 1.5 (0.) 0.15 (d.) 0.015 (e.) None of the above What is the gene order for these three loci? Circle the correct answer. (5 pts.) (21.) be a bac (c.) a be (d.) a c b (e.) None of the above Name What is the genetic distance (in map units) between the loci ab and be. Circle the correct answer. (5 pts.) (21.) 15 and 20 (b.) 20 and 15 (c.) 20 and 35 WE)“. 15 and 35 Ki; (e.) None of the above From the data shown above, what is the expected number of double crossover progeny resulting from this test cross? Circle the correct answer below. (5 pts.) @30 (b.) 35 (c.) 5 (d.) 15 (e.) None of the above From the number of observed and expected double crosser progeny, indicate the type of interference by circling the correct answer below. (5 pts.) (a.) absolute (b.) negative (0.) zero (none) @ partial (6.) None of the above 8. The measured distance between genes D and E in a two~factor test cross is 50 map units. What does this mean in physical terms? Circle the best answer. (8 pts.) A. D and E are on different pairs of chromosomes. B. D and E are linked and exactly 50 map units apart. ither D and E are on different pairs of chromosomes or D and E are linked and exactly 50 units apart. D. None of the above. ...
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This note was uploaded on 05/14/2011 for the course BIS 101 taught by Professor Simonchan during the Spring '08 term at UC Davis.

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BIS101-003_MT1_Key2 - y/ Name VUQY- Sl'om Z BISlOl-003,...

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