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Replication - DNA Replication It has not escaped our notice...

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1 DNA Replication “It has not escaped our notice that the specific pairing we have postulated immediately suggests a possible copying mechanism for the genetic material” 1 -Watson and Crick DNA Replication Models 2 Fig 3.1 Meselson and Stahl Experiment • Grow E. coli for many generations in 15 N media T f 14 N f i i Transfer to N for successive generations Following each round of replication, separate DNA with cesium chloride gradient Determine whether DNA molecules are heavy, light or hybrid 3 4 Figure 3.2
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