Chapter 17

Chapter 17 - Chapter17 PKU: AbnormalHemoglobin...

Info iconThis preview shows pages 1–2. Sign up to view the full content.

View Full Document Right Arrow Icon
Chapter 17 Dysfunctional Enzymes PKU:  neurological disease because of inability to convert phenylalanine to tyrosinase Abnormal Hemoglobin Sickle cell disease   first known disease due to amino acid abnormality 1 amino acid difference (gletamic acid replaced with valine) changed shape of protein Altered Membrane Proteins Some very common diseases are because of altered membrane receptors or transport  proteins Familial Hypercholesterolemia (FH):  blood cholesterol levels are much higher than  normal o can accumulate in inner walls of blood vessels   blood clots o unable to transport cholesterol to liver and other cells that use it cholesterol travels in LDLs   change receptor structure so it cannot bind  to LDL Cystic fibrosis:  unusually thick and dry mucus that line surface tissue such as airways  of respiratory system o Lack of functional membrane protein
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 2
This is the end of the preview. Sign up to access the rest of the document.

Page1 / 2

Chapter 17 - Chapter17 PKU: AbnormalHemoglobin...

This preview shows document pages 1 - 2. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online