polyketide_synthesis

polyketide_synthesis - CH 3 First cycle: OH AT , Acyl...

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OH OH O OH OH O OH O O CH 3 CH 3 OH CH 3 OH CH 3 O CH 3 OH CH 3 CH 3 SCoA O CH 3 OH CH 3 OH CH 3 O CH 3 CH 3 OH CH 3 OH CH 3 O SCoA CH 3 CH 3 S O R H CH 3 S O - R SCoA O CH 3 CH 3 S O R CH 3 O - CoAS CH 3 S O R 7 CH 3 1 O Polyketide Synthesis Requires Individual Enzyme Active Sites CH 3 S O KS AT KR ACP KS AT KR ACP TE KS AT KR ACP KS AT DH ER KR ACP R 6-Deoxyerythronolide B AT ACP KS AT KR ACP KS AT KR ACP
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Unformatted text preview: CH 3 First cycle: OH AT , Acyl transferase; ACP , Acyl carrier protein; KS , -Ketoacyl-ACP synthase; KR , -Ketoacyl-ACP reductase; ER , Enoyl reductase; TE , Thioesterase...
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