Chapter_6-08 - Chapter 6 Cell Organization: Systems Biology...

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1 1 Chapter 6 – Cell Organization: Systems Biology s Researchers study living organisms in terms of their underlying network structure rather than their individual molecular components s The goal is to understand how the organization of the cell arises by complex interactions between its various components and parts 2 All modern cells come from preexisting cell by division s All cells posses a genome s Living cells require pre-existing molecules s Cells require pre-existing organization
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2 3 Cell’s genetic information produces proteome s Information in most genes is used to make mRNA molecules that encode amino acid sequences of proteins s Study of individual proteins does not provide a broad integrated look at the dynamic nature of the cell 4 Genomes, proteomes and cell structure function and organization s The proteome is largely responsible for the structure and function of living cells s Gene and protein regulation causes the proteome to be dynamic s Proteins have sorting signals
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3 5 6 s Proteins often undergo protein-protein interactions s Cells must continually synthesize new molecules and break down unwanted components
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4 7 8 Molecular machines s A machine is an object that has moving parts and does useful work s These machines provide structure and organization to cells and enable them to carry out complicated processes s ATP synthase is a molecular machine that makes ATP b Molecular recognition allows for complex assembly s Subunits recognize each other and bind in a specific way
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5 9 10 Other molecular machines
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6 11 Cytoskeleton s Key role in cell organization and many processes that maintain the cell s Provides mechanical strength, cell shape, organization and direction to intracellular and cellular movements 12
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This note was uploaded on 05/18/2011 for the course BIOL 110 taught by Professor N/a during the Fall '08 term at University of Louisiana at Lafayette.

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Chapter_6-08 - Chapter 6 Cell Organization: Systems Biology...

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