Lecture1-mitosis&cell_cycle

Lecture1-mitosis&cell_cycle - Part II: Genetics The...

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Part II: Genetics – The basis of heredity FACT: Related individuals resemble each other more than randomly chosen individuals do Within populations Among populations within species Within species among species Etc. …WHY??
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Resemblance among relatives…”heredity” Information is passed from parent to offspring Information is passed largely intact That information encodes the phenotype Phenotype is any property of an organism that can be attributed to that organism (height, weight, eye color, obnoxiousness, etc.)
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Outline of today’s lecture – (Ch. 12) Review of (some) Eukaryotic cell structures Schematic overview of mitosis The mitotic spindle Cytokinesis Cell cycle control
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Review of Eukaryotic cell structures Nucleus Surrounded by membrane Contains the genetic material (DNA) During interphase, DNA uncoiled, complexed with proteins, called “chromatin” In mitosis, condenses into chromosomes
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Review of Eukaryotic cell structures Nucleolus Point of synthesis of ribosomal RNA Ribosomal subunits assembled Nucleolus
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Review of Eukaryotic cell structures Centrosomes Region near nucleus that is the cellular “microtubule organizing center” Associated with formation of spindle fibers Form “spindle poles” during mitosis
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Review of Eukaryotic cell structures Cytoskeleton Provides mechanical support to the cell Dynamic (disassemble and reassemble) Constructed of microtubules , microfilaments, intermediate filaments
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Microtubules: Structure and Function Composed of polymers of dimers of α-tubulin, β- tubulin Lengthen by adding dimers, shorten by losing dimers “Molecular motors” can move along microtubules
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Mitosis and the Cell Cycle All organisms must grow and reproduce During organismal growth, all cells must grow and divide
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This note was uploaded on 05/19/2011 for the course BSC 2010 taught by Professor Bowes during the Spring '08 term at University of Florida.

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Lecture1-mitosis&cell_cycle - Part II: Genetics The...

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