16. Early Embryo Develop '10

16. Early Embryo Develop '10 - Early Early Embryonic...

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Early Early Embryonic Embryonic Development Development
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Zygote - Embryo Zygote - Embryo • two gametes fuse to produce zygote • with first division embryo is produced
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Cleavage Cleavage A series of mitotic divisions whereby a multicellular organism is formed – Cells produced are called blastomeres – Controlled by maternal mRNA and protein in most species – Most species = no net gain in volume • allows rapid division • is accomplished by skipping the G1 and G2 growth period between mitotic divisions
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Mitosis Promoting Factor Mitosis Promoting Factor • Regulates biphasic cycle of early blastomeres • Made up of two subunits – Cyclin B : accumulates during S phase and degrades following M phase – Cyclin-dependent kinase (cdc2): phosphorylates key proteins involved w/ mitosis
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Cleavage Cleavage • Rapid exponential increase in cell # – Frog egg divides into 37,000 cells in 43 hrs • 1 cleavage/hr – Drosophilia-50,000 cells in 12 hrs • 1 division every 10 mins for 2 hrs • Initially synchronous until mid-blastula transition – Growth phases added – Synchronicity lost – New mRNA transcribed
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Rate of formation of new cells in the frog Rana pipiens
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This note was uploaded on 05/19/2011 for the course ZOO 4926 taught by Professor Staff during the Summer '08 term at University of Florida.

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16. Early Embryo Develop '10 - Early Early Embryonic...

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