Cancer and signaling - Cancer Cancer Cells Reproduce...

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Cancer Cells Reproduce Without Restraint and Colonize Other Tissues Cancer Figure 20-1. Metastasis Patient= metastatic non-Hodgkins lymphoma Background=CT(computed X-ray tomography scan PET (positron emission tomography)- detects uptake of radioactive flurodeoxygluecose reveals tumor tissue Yellow spots in abdomen= metastases malilgnant=invades surrounding tissue(enters blood or lymphatic tissue Tumor (neoplasm=new growth)
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Figure 20-3 Benigin glandular tumor (adenoma) Most Cancers Derive from a Single Abnormal Cell Carcinoma= cancers arising from epithelial cells Sarcoma= cancers arising from connective tissue or muscle cells Leukemia and lymphomas= arise from white blood cells and their precursors •Cancers Develop Gradually from Increasingly Aberrant Cells •Cancer Cells Contain Somatic Mutations
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Figure 20-8. Delayed onset of cancer following exposure of 78 workers exposed to 2-naphthylamine.
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•A Single Mutation Is Not Enough to Cause Cancer Figure 20-9. Progression of cancer of the epithelium of the uterus Stratified squamous Diving cells confined to Basal layer Dividing cells in lower 1/3 of epithelium Cells dividing in all layers Cells move through or destroy the basal lamina
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A Single Mutation Is Not Enough to Cause Cancer Tumor Progression Involves Successive Rounds of Random Inherited Change Followed by
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Cancer and signaling - Cancer Cancer Cells Reproduce...

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