cancer - Click to edit Master subtitle style Cluster...

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Click to edit Master subtitle style 5/20/11 Cluster analysis of networks generated through Team 1 Author: Kirill Osipov Presenter: Ferhat Ay
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5/20/11 Background Metastasis is an event associated with a poor prognosis in cancer patients Metastasising cancer cells break away from the primary tumor acquire increased motility and
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5/20/11 PPI network analysis methods 1. Experimental, biochemical analysis Microarray gene expression data provides correlation between gene expressions lacks information on protein interaction mechanism Genome survey High throughput but error prone
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5/20/11 Computational PPI analysis Protein interaction network is composed of predictions of individual PPIs prediction score is assigned to each interaction higher score => higher prediction confidence
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5/20/11 Paper(Jonsson et al) Created a protein interaction network, "interactome" for a rat used computational and homology* approaches developed a scoring function based on
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This note was uploaded on 05/20/2011 for the course CAP 5515 taught by Professor Ungor during the Spring '08 term at University of Florida.

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cancer - Click to edit Master subtitle style Cluster...

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