MS-240notes - MASS SPECTROMETRY analytical tool used for...

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MASS SPECTROMETRY analytical tool used for measuring the molecular weight of a sample for large samples such as biomolecules , molecular weight can be measured within an accuracy of 0.01% of the total molecular weight of the sample
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Structural information can be generated using certain types of mass spectrometers, usually tandem mass spectrometers achieved by fragmenting the sample and analysing the products generated useful for the structural elucidation of organic compounds , for peptide or oligonucleotide sequencing, and for monitoring the existence of previously characterised compounds in complex mixtures
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INTERPRETATION OF MASS SPECTRA obtain a good spectrum evaluate the general appearance find the molecular ion identify the structural feature
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Biotechnology : the analysis of proteins, peptides, oligonucleotides Pharmaceutical : drug discovery, drug metabolism Clinical : neonatal screening, haemoglobin analysis, drug testing Environmental : water quality, food contamination Geological : oil composition
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MS-240notes - MASS SPECTROMETRY analytical tool used for...

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