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1 pair of c hromosomes = 2 t ypes of gametes 2 pairs of c hromosomes = 4 t ypes of gametes The number of different types of gametes that are possible as the result of independent assortment of parental c hromosomes is 2^n Humans, therefore, c an make 223 (about 8 million) different t ypes of gametes due to independent assortment of parental c hromosomes alone I nteraction of the s pindle ﬁ bers with the c hromosomes occurs during prometaphase I. The kinetochore microtubules link one of the homologous chromosomes to one of the poles, while a second set of kinetochore microtubules link the other homologous chromosome to the other pole (Figure 3.13). At metaphase I, each bivalent pair may align in one of two configurations (Figure 3.12). The number of different, random alignments for a species is equal to 2n, where n equals the number of chromosome pairs. During anaphase I (Figure 3.12) the homologous chromosomes separate from each other and begin to migrate to opposite poles. The sister chromatids remain connected during Meiosis...
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