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Reproduction and Chromosome Transmission

6 at this point the cell has twice as many chromatids

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Unformatted text preview: At this point the cell has twice as many chromatids compared to the number of chromosomes in the G1 phase (46 pairs of sister chromatids in humans). After chromosome replication (and, hence, DNA replication), the cell enters G2 phase during which it continues to grow and completes preparations for cell division (e.g., replication of the centrosome) In M phase (mitosis) the cell distributes the replicated chromosomes so that each of the new daughter cells has an exact complement of chromosomes that were found in the original cell. Mitosis was first described in the 1870s by Walter Flemming, who noticed that during cell division each of the daughter cells received an exact copy of the threads (chromosomes) he was observing under the microscope. The mitotic spindle apparatus organizes and sorts eukaryotic chromosomes. The mitotic spindle apparatus is involved in the organization and sorting of chromosomes so that each daughter cell receives the same complement of chromosomes (Figure 3.7)....
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