Reproduction and Chromosome Transmission

Polar microtubules project to the region between the

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Unformatted text preview: ar microtubules project to the region between the two spindle poles where the chromosomes will be found during mitosis; ones that overlap one another play a role in separation of the two poles. Kinetochore microtubules have attachments to the kinetochore and operate in separation of the chromosomes to opposite poles of the cell. The interaction of the spindle fibers with the chromosomes occurs during prometaphase (Figure 3.8c). Once a kinetochore microtubule comes in contact with the kinetochore, it is captured and no longer moves. Kinetochore microtubules connect to the kinetochore from both poles of the cell, and gently tug the chromosomes back and forth during prometaphase. Metaphase occurs when the chromosomes align along a central plane called the metaphase plate (Figure 3.8d). The sorting of the chromosomes occurs during anaphase (Figure 3.8e), when the connection between the sister chromatids breaks. At this point each of the chromatids is linked to only one of the poles. Each chromatid is now considered to be an independent chromosome. The...
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