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Chapter21 - BCH 4054 Chapter 21 Lecture Notes Slide 1...

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Chapter 21, page 1 BCH 4054 Chapter 21 Lecture Notes Slide 1 Chapter 21 Electron Transport and Oxidative Phosphorylation Slide 2 Overview Oxidation of NADH and CoQH 2 produced in TCA cycle by O 2 is very exergonic. Some of the energy of oxidation is captured by synthesis of ATP from ADP and P i The capture of energy requires a “coupling” of oxidation to phosphorylation Coupling occurs through an intermediate proton electrochemical gradient across the inner mitochondrial membrane. Slide 3 Energetics of Redox Reactions Oxidation-Reduction (Redox) reactions can be written as two “half-cell” reactions. A ox + B red A red + B ox can be written as the sum of: A ox + e A red and B red B ox + e These “half-cell” reactions can be physically separated and the electron transferred by an electrical circuit. (See Fig 21.2)
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