test2(1)

test2(1) - BCH 4054 October 8, 1999 HOUR TEST 2 NAME_...

Info iconThis preview shows pages 1–3. Sign up to view the full content.

View Full Document Right Arrow Icon
BCH 4054 October 8, 1999 HOUR TEST 2 NAME_____________________ Points 1. The stimulation of glycogen breakdown by hormones was the first experimental system in which a "second messenger" signaling pathway was demonstrated for the ultimate activation of the enzyme phosphorylase . This pathway acts as a "cascade" in that the product in each step is a catalyst for the next step, resulting in an amplification of the signal. Page Points 1 ____ 2 ____ 3 ____ 4 ____ Total ______ (8) (a) Diagram this signaling pathway for liver , indicating all the intermediate steps and intermediates from the first interaction of the hormone with the cell to the covalent modification of phosphorylase. (4) (b) What is the identity of the "second messenger" in this scheme (draw its structure), identify the protein it activates, and describe how it interacts with that protein. (6) (c) Name three other enzymes in liver whose activities are affected by covalent modification stimulated directly or indirectly by this second messenger. For each, indicate whether each enzyme is activated or inhibited .
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
BCH 4054 --Hour Test 2 Page 2 Name________________________ 2. In the presence of cyanide and excess cytochrome c, mitochondria can carry out the following reaction (where the NADH is generated from oxidation of substrates via the
Background image of page 2
Image of page 3
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 05/22/2011 for the course BCH 4054 taught by Professor Logan/gilmer during the Spring '06 term at FSU.

Page1 / 4

test2(1) - BCH 4054 October 8, 1999 HOUR TEST 2 NAME_...

This preview shows document pages 1 - 3. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online