This preview shows pages 1–2. Sign up to view the full content.
This preview has intentionally blurred sections. Sign up to view the full version.View Full Document
Unformatted text preview: Organic Syntheses, Coll. Vol. 1, p.457 (1941); Vol. 2, p.75 (1922). PHTHALIMIDE Submitted by W. A. Noyes and P. K. Porter. Checked by H. T. Clarke and J. H. Bishop. 1. Procedure ( A ) In Pyrex 5-l. round-bottomed flask is placed a mixture of 500 g. (3.4 moles) of phthalic anhydride and 400 g. (444 cc., 6.6. moles) of 28 per cent aqueous ammonia . The flask is fitted with an air condenser not less than 10 mm. in diameter and is then slowly heated with a free flame until the mixture is in a state of quiet fusion at a temperature of about 300 (Note 1) . It requires about one hour before all the water has gone and about one and one-half to two hours before the temperature of the reaction mixture reaches 300 and the mixture is a homogeneous melt. It is advisable, during the heating, to shake the flask occasionally; some material sublimes into the condenser and must be...
View Full Document