3.herat

3.herat - Cardiovascular physiology 1: the heart Outline...

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Unformatted text preview: Cardiovascular physiology 1: the heart Outline The heart as a pump 1) cardiomyocytes and cardiac muscle 2) blood flow through the heart 3) pacemakers and the conduction system 3) pacemakers and the conduction system 4) cardiac muscle action potentials ) rdiac cycle 5) cardiac cycle 6) regulation of cardiac output: heart rate and stroke volume HKin 191 1 7) exercise and the heart Cardiovascular physiology I: the heart Key concepts How and when the heart contracts How and why cardiac muscle differs from skeletal muscle How heart rate is set: action potentials and the role of the pacemaker The cardiac conduction system and the spread of pacemaker potentials ardiac muscle cell action potentials and contraction Cardiac muscle cell action potentials and contraction Getting the blood in and out he cardiac cycle The cardiac cycle Controlling the heart (CO = HR x SV) Heart rate and contractility HKin 191 2 Neurons and hormones, chemicals and drugs Cardiovascular physiology 1: the heart The standard anatomical position • • Dextrocardia: tus inversus situs inversus : HKin 191 3 1) Cardiomyocytes and cardiac muscle Cardiac muscle is similar to skeletal muscle but: ) 1) 2) 3) 4) HKin 191 4 5) 1) Cardiomyocytes and cardiac muscle Low resistance pore “Connexon” Proteins (6 on each side of membrane) HKin 191 5 1) Cardiomyocytes and cardiac muscle- - - - - - - - - - - - - - - - - - - - - -- - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + Cardiac muscle is similar to skeletal muscle but: ____ mV free flow of ions through pore in nnexons tosol _____ mV- - - - - - - - - - - - - - - - - - - -- - - - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + connexons cytosol electrical potential maintained by _______________________ gap junctions are _________ more conductive than cell membrane HKin 191 6 ____________ _____________ _______ 2) Blood flow through the heart Mammalian heart has ___ chambers: Left side: A LA Right side: RA V LV RV HKin 191 7 ystemic drainage (BODY) 2) Blood flow through the heart Systemic drainage (BODY) b right atrium b tricuspid valve (TV) b right ventricle b pulmonary valve (PV) b b pulmonary trunk b pulmonary arteries b pulmonary circulation b lungs b o systemic To pulmonary circulation To systemic circulation RA LA Pulmonary drainage Systemic drainage av pv tv bv Pulmonary drainage (LUNGS) ulmonary veins ft auricle/atrium icuspid valve (BV) ft ventricle RV LV HKin 191 8 b pulmonary veins b left auricle/atrium b bicuspid valve (BV) b left ventricle b aortic valve (AV) b arch of aorta b systemic circulation b 3) Pacemakers and the cardiac conduction system The basics: rdiac muscle contain ___________ • cardiac muscle contain ___________ acemakers are ___________________________ • pacemakers are ____________________________ • pacemakers set ___________________________________ HKin 191 9 Heart will beat in the absence of: 3) Pacemakers and the cardiac conduction system...
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This note was uploaded on 05/21/2011 for the course BHK 191 taught by Professor Jim during the Spring '11 term at UBC.

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3.herat - Cardiovascular physiology 1: the heart Outline...

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