5.pulmon - HKin 191 1 Outline 1) Respiration and...

Info iconThis preview shows pages 1–10. Sign up to view the full content.

View Full Document Right Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: HKin 191 1 Outline 1) Respiration and ventilation 2) Pressure changes and airways 3) Lung volumes and capacities 4) Gas exchange, hemoglobin, O 2 and CO 2 transport 5) Regulation of breathing Section 3: Pulmonary physiology HKin 191 2 Key concepts The nature of gases • partial pressures in the air, lungs and blood How air is moved in and out of the lungs • pressure changes and flow - Poiseuille’s law (again) How gas molecules move: lungs b blood b tissue • diffusion - Fick’s law (again) How blood gases are monitored How supply is determined by demand • by regulating respiration (breathing) and transport (hemoglobin) • matching supply to demand during exercise Section 3: Pulmonary physiology HKin 191 3 1) Respiration and ventilation • movement of air (gases) from external environment b lungs • movement of air (gases) from the lungs b external environment • automatic, rhythmic, constant and regulated ~12 bpm (breaths/minute), or 473 million breaths/lifetime each breath ~500 ml (6 liters/min) about 240 million liters/lifetime Breathing: getting the air in and out HKin 191 4 • internal respiration: • external respiration: in mammals: done via exchange surfaces in lungs (mostly) Respiration 1) Respiration and ventilation HKin 191 5 • flow of blood to respiratory exchange regions of lungs (external respiration) • Pulmonary perfusion (pulmonary circulation): • flow of blood to tissues (internal respiration) • Systemic perfusion (systemic circulation): 1) Respiration and ventilation Perfusion: getting the blood in and out HKin 191 6 Gases and partial pressures 1) Respiration and ventilation • “air” is a mix of gases • weight of air causes atmospheric pressure • atmospheric pressure varies with altitude • atmospheric pressure at sea level = _______________________ HKin 191 7 • air is a mixture of gases: 21% O 2 79% N 2 0.03% CO 2 + trace gases + moisture (humidity) • F n = fraction of gas n in the mix ( e.g. FO 2 of air = 21%) Gases and partial pressures 1) Respiration and ventilation HKin 191 8 • sea level atmospheric pressure = 760 mmHg • fraction of each gas contributes proportionately to overall pressure • P n = pressure of gas n (or partial pressure of gas n in a mixture) Dalton’s law: If atmospheric pressure = 760 mmHg at sea level then PO 2 = 21% of 760 mmHg = ____________ PN 2 = 79% of 760 mmHg = __ ____________ Gases and partial pressures 1) Respiration and ventilation HKin 191 9 Gases and partial pressures at altitude P atm at the summit of Mt. Baker (3285 meters) = 502 mmHg PO 2 = 105 mmHg 1) Respiration and ventilation P atm at Everest Base Camp (5340 meters) = 380 mmHg PO 2 = 80 mmHg P atm at Everest summit (8850 meters) = 250 mmHg PO 2 = 52 mmHg What is FO 2 at Everest summit?...
View Full Document

This note was uploaded on 05/21/2011 for the course BHK 191 taught by Professor Jim during the Spring '11 term at The University of British Columbia.

Page1 / 101

5.pulmon - HKin 191 1 Outline 1) Respiration and...

This preview shows document pages 1 - 10. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online