190lec9 neurophys - 9 Neural Physiology: Neural...

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Unformatted text preview: 9 Neural Physiology: Neural Transmission and Sensory Receptors HKIN 190: Anatomy and Physiology I Learning Objectives: 1. To understand what a synapse is and what comprises it. 2. To understand the events at the neuron-to-neuron synapse. 3. To understand the events at the neuron-to-muscle cell synapse. 4. To understand the classification of sensory receptors. 5. To become familiar with specific somatic sensory receptors, including: 1. cutaneous (skin) receptors for touch, pain/temp 2. muscle receptors for proprioception 6. To understand the properties of sensory receptors. Tissue types in the body CMEN C onnective Tissue Blood Bone Cartilage Connective Tissue Proper M uscle Smooth Skeletal Cardiac E pithelial Squamous Cuboidal Columnar Pseudostratified Transitional N ervous To understand what a synapse is and what comprises it. Learning Objective 1 What other cells do nerve cells connect or synapse with? Neurons can connect with: 1. other neurons electrical synapses (gap junctions) chemical synapses 2. Muscle cells neuromuscular junction 3. glands Review the pathway of neural transmission (sensory interneuron motor) 3 parts to this connection or synapse 3 parts: 1. axon terminal of pre-synaptic neuron 2. synaptic cleft space between cells 3. membrane of post-synaptic cell dendrites(neuron) motor end plate (muscle cell) To understand the events at the neuron-to-neuron synapse. Learning Objective 2 Neuron-to-neuron synapses Where is the neuron-neuron synapse happening? Steps involved in synap/c transmission : 1) the ac/on poten/al travels from the trigger zone, down the axon, down the axon terminals and Fnally arrives at the synap&c end bulb 2) here, the depolariza/on triggers the opening of voltage-gated Ca 2+ channels (in addi/on to the Na + channels that normally open during depolariza/on) Events at the synpase cont Events at the synpase cont Events at the synpase cont Events at the synpase Neurotransmitters and receptors whether a neurons postsynaptic effect is excitatory or inhibitory is determined by the relationship between a neurotransmitter and the postsynaptic receptor Example: acetylcholine (ACh) can be either excitatory (eg: when a neuron synapses with a skeletal muscle cell) or inhibitory (when a neuron synapses with a cardiac muscle) receptors...
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This note was uploaded on 05/21/2011 for the course BHK 190 taught by Professor Janice during the Spring '11 term at The University of British Columbia.

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190lec9 neurophys - 9 Neural Physiology: Neural...

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