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Cells1 - Lecture Objectives-to better understand cell...

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1 Lecture Objectives: -to better understand cell metabolism - the set of reactions in an organism that collectively… 1. allow cells to transport molecules in and out of their membrane boundaries 2. allow cells to respond to changes in their external environment 3. allow cells to use genetic information to build large molecules for structure and function 4. allow cells to move and target molecules through their interior volume 5. allow cells to utilize and transform energy for all of the above Cells in all three domains of life share certain characteristics Membrane - a fluid, mosaic, selectively permeable barrier allowing flow inside and outside of the cell INSIDE OUTSIDE Figure 1.7 phospholipids proteins Membranes: 1. Serve as barrier 2. Control flow 3. Receive signals 4. Transmit signals Adapatation: What Controls Membrane Fluidity under changing conditions? Hybernating Wood Frog Video interlude (Inner Life of the Cell) Saturated fatty acids more solid (warm) Unsaturated fatty acids more liquid (cold) Cholesterol (animals) How do molecules get in/out of cells? Diffusion random motion of particles that causes them to spread in a time-dependent manner Gradient- spatial variation in concentration of a chemical or charge that leads to a net flow Diffusion through cell membranes favors: Small > Big Uncharged > Charged Non-polar > Polar
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2 Passive transport - flow down a gradient through for impermeable molecules thru… 1. Channels (pores) - proteins that allow big, polar
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