4-ProteinsEnzymes

4-ProteinsEnzymes - Proteins and Enzymes Proteins and...

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1 1 Proteins and Enzymes Dr. Beth Dawson BIO 3, Fall 2010 San José State University 2 Proteins and Enzymes 1. Protein shapes 2. Protein functions 3. Protein structure 4. Enzymes 5. Regulation of enzymes 3 Protein • Shape – Globular or fibrous • Structure – 3 or 4 levels of structure determine shape, activity, conformation 4 Protein Shapes Globular – Complex shapes, usually soluble in water – Variety of functions – Examples: enzymes, transporters, regulatory Fibrous – Long filaments, mostly not soluble in water – Function is generally structural – Examples: Keratins, collagens, elastins 5 Protein Functions • Enzymes • Structure • Transport • Motility • Storage • Signals • Receptors • Gene regulation • Many, many other functions 6 Connective tissue Fibrous protein Most abundant protein in mammals
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2 7 Metalloprotein Contains iron Red blood cells Gas transport 8 Enzyme Breaks phosphodiester bonds between adjacent nucleotides in DNA 9 Hormone Causes cells to import glucose from the blood 51 amino acids 10 Amino Acids 11 Protein Structure • Primary – Sequence of amino acids – Covalent peptide bonds • Secondary – H bonds between backbone – Alpha helix, beta pleated sheet 12 Protein Structure • Tertiary – Between R groups of amino acids H bonds, hydrophobic forces, van der Waals forces, ionic bonds, disulfide bridges • Quarternary – Association of subunits into final protein – Not always
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3 13 Primary Structure
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This note was uploaded on 05/24/2011 for the course BIO 3 taught by Professor Dylan during the Spring '11 term at Evergreen Valley.

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4-ProteinsEnzymes - Proteins and Enzymes Proteins and...

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