10-ProteinTrafficking

10-ProteinTrafficking - Intracellular Transport Protein...

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1 1 Intracellular Transport Protein Sorting and Secretion Chapter 15 Dr. Beth Dawson BIO 3, Fall 2010 San José State University 2 Figure 15-2 Essential Cel Biology (© Garland Science 2010) 3 Table 15-1 Essential Cel Biology (© Garland Science 2010) 4 Review - Transcription, Translation 5 After translation • 3 destinations for proteins – Cytosol – Organelles - inside or in membrane – Out of cell or in cell’s outer membrane (facing in or facing out) 6 Figure 15-5 Essential Cel Biology (© Garland Science 2010)
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7 Signal sequences • Structure – Amino acid sequence at N terminus – Properties • Positive vs negative charge, hydrophobic vs hydrophilic 8 Signal sequences • Structure • Function – Target trafficking of proteins – Necessary and sufficient – Physical properties of amino acids more important than exact amino acids 9 Figure 15-13 Essential Cel Biology (© Garland Science 2010) 10 Figure 15-14 Essential Cel Biology (© Garland Science 2010) 11 Figure 15-15
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This note was uploaded on 05/24/2011 for the course BIO 3 taught by Professor Dylan during the Spring '11 term at Evergreen Valley.

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10-ProteinTrafficking - Intracellular Transport Protein...

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